In the field of plant engineering, a significant shift towards sustainable engineering is underway, emphasizing the integration of innovative solutions and new standards. The redesign of cleanroom technology is highlighted, enabling new perspectives in planning. Key focus areas include sustainable product development, reuse concepts, and the circular economy, all underscored by the critical role of standardization and process parameters. The CO2 equivalent is increasingly viewed as a pivotal indicator for more environmentally conscious actions in this sector.