Leaks during processing are unfortunate but a reality in pharmaceutical manufacturing facilities using single-use technology. They represent a hazard to the product quality and safety since there is the opportunity for contamination. Through a final risk-based evaluation a decision is taken to continue or discard a batch. Since it is not possible to fully demonstrate that a contamination did not occur, the higher the risk to the product, the more likely it will be discarded. This presentation will offer a novel perspective on leaks and the associated product contamination risk to avoid the need to discard the material or product.