14.01.2026
Multi-port valve block used as a filter base
Elena Zuck
GEMÜ Gebr. Müller Apparatebau GmbH & Co. KG

In aseptic production plants, additional process valves, fittings or further connections are often required in the area around filters. For process engineering reasons, a sterile steam supply and a condensate drain must be provided, e.g. for
sterilization of the filter. It must also be possible to carry out the integrity tests required by the authorities on filters. These process valves or fittings are generally welded onto the filter base itself either individually or in prefabricated subassemblies. It is advisable to manufacture the entire filter unit, comprising filter base, valves, fittings and connections, from a block material – namely stainless steel block. This minimizes the installation space and removes the need for time-consuming welding work.  

For the most varied applications, GEMÜ develops custom filter bases, tailored to
customer requirements, e.g. for bioreactors. Configuring filter bases this way
makes PUPSIT filter tests (Pre-Use Post Sterilization Integrity Test) easier to
perform.  

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Elena Zuck
GEMÜ Gebr. Müller Apparatebau GmbH & Co. KG