
Gold Series Camtain for pharmaceutical manufacturing application
Benefits
Health and Safety considerations
Two key concerns are critical when handling pharmaceutical dusts: the potent, toxic or allergenic properties of the compound as it relates to personnel exposure and the explosion properties of the compound.
Health and Containment
The first issue involves understanding the toxicological properties of the material, reviewing the occupational exposure limit (OEL) and performing a risk-based exposure evaluation to determine the methods for proper control. In most cases, some level of isolation and containment is required due to the fact that the pharmaceutical dust is extremely potent while being captured in a non-production area. Therefore, it cannot be released into the surrounding environment.
In most cases, Camfil APC recommends a HEPA secondary polishing system. With HEPA backup systems and the dust collector, recirculation of the filter air back into the HVAC system is possible. This can significantly reduce energy costs while providing the necessary level of filtration for discharge air required by the EPA.
Safety
The second concern involves deflagration and explosion potential. Control measures such as explosion venting, chemical suppression and isolation systems may be required depending on the physical characteristics of the dust relating to Kst, MIE and the location of the collector.
When explosion vents are required, they must be vented to the outside by either placing the collector outdoors or ducting the vent exhaust a specified distance through the building structure. To prevent outdoor or off-property exposure in the event of a dust explosion of potent compounds, either chemical suppression or containment designs for explosion and isolation valves are preferable to venting. The reason why is because these two protection options do not release materials to the environment.
Camfil APC recommends that an independent PE specifies what explosion protection is required for a given material as it relates to standards in NFPA, ATEX and the major insurance carriers.
Learn more at www.camfil.com.