Weighing of highly active substances in sterile production
Weighing of Highly Active Substances in Pharmaceutical Production: • Introduction by Bernhard Steidle and Dirk Collins • What Does “Highly Active” Mean? • What Do OEL/OEB/BIEL Stand For? • How Is the OEL Measured? Brief description of an SMEPAC test • Case study: Boehringer Ingelheim Biopharma Biberach • Process description • Special considerations for highly active substances. What needs to be considered during feeding, cleaning, […]
MTP-Standardized Automation for the Future of Manufacturing
The production of the future requires maximum flexibility: products have to be manufactured in ever shorter times and often in small batches. This means rapid adaptation, modular device integration and the shortest possible conversion times in order to avoid downtimes. RETEL Neuhausen AG uses a practical example to show how standardized, modular automation solutions can be implemented using MTP (Module Type Package) [...].
FactoryLayer© - "Next Generation" - GMP Monitoring
With the FactoryLayer© GMP Monitoring System FL-EMS, RETEL Neuhausen AG has a scalable GMP monitoring system that can be optimally adapted to the customer's needs. The FL-EMS system is characterized by its multidimensional scalability in the following disciplines: - Sizing: Rooms | Floors | Buildings | Campus | Company-wide - Data sources: Sensors [...]
Energy Savings in Ventilation and Air Conditioning
The presentation describes the potential for saving electrical energy in the ventilation and air conditioning of cleanrooms. Cleanrooms often require very high airflow rates, which in turn result in high energy consumption. Therefore, pressure losses must be reduced, and component efficiency should be maximized. The presentation outlines the key factors for reducing energy consumption and presents possible solutions […]
Benefits & limits of the heat recovery system compared to the heat pump
This technical presentation examines the benefits and limitations of heat recovery compared to heat pumps in the context of the energy transition. Addressing the question of whether waste heat utilization makes sense only with heat pumps, our expert considers a combination of both technologies to be a sensible and sustainable solution. The comprehensive presentation explores various scenarios, challenges, and opportunities. […]
Cleanroom Construction in Existing Buildings – Innovative Solutions
Presentation of a project procedure for the implementation of a clean room in an existing building. Reduction of implementation time and CO2 emissions when integrated into existing buildings. Project-specific solution finding and continuous adaptation to emerging tasks of the existing property with high flexibility of all parties involved. This requires constant review and comparison with the customer's defined requirements. Complex integration of existing installations, [...]
Optimization of heat recovery
The presentation describes the potential for saving electrical energy during part-load operation in the ventilation and air conditioning of cleanrooms equipped with fan walls. Fan walls consist of a large number of fans that supply air to the cleanroom in parallel. The first part of the presentation demonstrates that there is an optimal number of fans to be used for ventilation when designing the system. In […]
One Ansell, one future: promoting personal protection
Case Study: Enzyme Indicators—Practical Applications
Isolator technology is playing an increasingly important role, particularly in the manufacture of biopharmaceutical products and advanced therapy medicinal products (ATMPs). To ensure aseptic conditions, hydrogen peroxide (H₂O₂) is frequently used for decontamination. In addition to established chemical and biological indicators (BI & CI), enzyme indicators (EI) are also gaining increasing attention. EI are based on the inactivation of an enzyme through […]