CryoRoadstar low-temperature trailer from -30 to -110°C
The low-temperature trailer is a standard system, including storage system, safety, loading and unloading concept. The trailer consists of special insulation panels with PU foam, which are mechanically stable enough for extreme temperatures and achieve a sufficient insulating effect for the low temperature range. For the main storage room, we used Mirai Intex's flexible cold air chillers, which can withstand temperatures from -40°C to -110°C (optionally up to [...]
Hard to kill bugs, resistance to irradiation & disinfection
Hard to Kill Bugs - Resistance to irradiation and disinfection in microorganisms There are more microorganisms that survive sterilization and disinfection processes than is generally assumed. This fact is increasingly taken into account in regulatory documents. It must be possible to assess the risk of finding such microorganisms in the manufacturing process. This requires a precise understanding of the bioburden before the [...]
CO2 footprint in cleanroom technology
Cleanroom technology in the classic sense, and thus the entire infrastructure and air technology in focus, is still predominantly built and operated on the basis of traditional regulations and old practices. In times of modern simulation technology, optimized measurement and control technology and pressure to save energy, there is an opportunity to implement energy-optimized cleanroom systems and facilities. For example, [...]
Conversion of existing buildings
Prudent planning before interfering with existing buildings Converting existing buildings to a new use is difficult but not impossible. The conversion, renovation or extension of existing buildings requires precise project development. Legal regulations must match the structural conditions. This starts with the room height, which must fit despite subsequent installations, and ends with the load-bearing capacity [...]
BCSU - World's first germ collection head with integrated agar
How can I easily switch from random sample measurement to continuous measurement without changing the measurement methodWhy air velocities play a role in microbiological measurementWhat must be considered when changing agar plates and how can I avoid false positives when changing agar platesWhy are sedimentation plates not state of the art in an ISO 5 environment?
FMS system
The world's most widely used cleanroom monitoring system with buffer process and dual processor on separate working levels. Never again experience a data failure in production due to a PC error.
Deep freezer - PQ to monitoring
The qualification of cooling appliances is becoming more present in the pharmaceutical sector. The devices have become indispensable for the storage of pharmaceutical substances such as vaccines. Find out what is useful for initial qualification and what the life cycle looks like with requalification and monitoring.
GMP and GDP - a strong team!
Product quality and patient safety are the goal! But how do you get there? The production of pharmaceuticals according to the rules of GMP (Good Manufacturing Practice) and their distribution according to the rules of GDP (Good Distribution Practice) work hand in hand as a strong team to maintain the required product quality and thus ensure the safety of [...]
HOF Freeze-Thaw Unit: Innovative cooling technologies
Controlled freezing and thawing of pharmaceutical and biotechnological processes is an integral part of many processes today. The HOF Freeze-Thaw Unit offers the possibility of effective and controlled process management. Current challenges of the refrigeration system of the unit are directly linked to the F-Gas Regulation. HOF has developed its Freeze-Thaw Units with various innovative but also sustainable [...]
Training as the basis for purity-compliant product
The appropriate interplay between cleanroom, personnel, material flow, process, cleaning and reagent technology is the prerequisite for the production of high-quality, contamination-sensitive products. The basis for this is an understanding of the type and quantity of critical contaminants. Based on this, the necessary and target-oriented technical and operational measures for generating and maintaining product purity can be selected. A [...]