Personnel access impacts workflows and cleanliness levels. Proper planning and design are essential for efficient and cleanroom-compliant gowning. Beyond personnel pathways, it is crucial to consider the supply and disposal of garments. Using real-world examples of personnel airlocks designed for pharmaceutical clients, this presentation showcases solutions that optimize throughput, address future needs, and meet regulatory standards. A special focus is placed on the new Annex 1 requirements, with practical approaches for proper implementation.