In view of the growing demand for pre-sterilized RTU components such as syringes and vials, ebeam technology is being used increasingly. By sterilizing surfaces, it enables these components to be transferred to Class A cleanrooms, such as isolators. According to the specifications of Annex 1, the transfer of materials into and out of cleanrooms and critical zones represents one of the greatest sources of contamination. Where possible, objects should be sterilized before being transferred to such areas. The presentation provides an introduction to the functionality and application of ebeam technology.