The presentation “Annex 1: Big words, small media-fill-actions” calls for a fundamental rethink in the handling of media-fill tests. Despite their central role, they often remain formal mandatory exercises rather than genuine performance indicators of sterile processes. The new Annex 1 offers the opportunity to use media fill strategically—as a continuous learning and improvement tool. The presentation shows how companies can move beyond mere compliance, systematically uncover weaknesses in process design, and actively shape quality.